Methods The 28 day in vivo method recommended by WHO for effect test of antimalarial drugs in middle and low endemic area of malaria was applied in the observation.

• 方法按照WHO推荐的在中低度疟疾流行区抗疟药治疗效果的28天随访观察法。对单纯氯喹治疗判定为早、晚期治疗失败的恶性疟病人进行治疗。