Methods Studies were made on endogenous NO,biochemical changes of cholestasis,liver mitochondrial function and renal excretion in a rat model at different time points after ANIT administration.

• 方法利用ANIT诱发大鼠肝内胆汁淤积的模型，动态观察内源性NO、肝内胆汁淤积生物化学改变、肝组织线粒体功能和肾排泄的变化。