Methods Starting from 2,6-dichloropyridine, tenatoprazole was obtained via seven steps, such as nitration, ammoniation, substitution, reduction, cyclization, alkylation, and oxidation.

• 方法以2,6-二氯吡啶为起始原料，经硝化、氨解、取代、还原、环合、烃化、氧化7步反应合成泰妥拉唑(1)。