Methods PCRSSCP and DNA sequencing were used to analyze the PTCH gene mutations in 12 OKCs,including 10 sporadic and 2 nevoid basal cell carcinoma syndrome(NBCCS) associated OKC.

• 方法采用PCR-SSCP筛查与DNA直接测序的方法对12例OKC进行PTCH基因突变的检测,其中2例为痣样基底细胞癌综合征(NBCCS)相关OKC,10例为散发OKC。