Methods Longitudinally followed up 118 cognitively normal elderly, compared their annual MMSE changes, incidence of dementias with APOE4 genotypes and vascular risk factors.

• 方法对118例认知功能正常的老年人进行随访,观察简易智能状态检查(MMSE)评分的改变和痴呆发生率与APOE基因型以及血管性风险因子的关系。