Methods HIE was induced in rats on 7th day of postnatal age by ligation of right common carotid artery,followed by 2 h of hypoxia(80 mL/L O2).

• 方法新生鼠HIE模型为7日龄新生鼠,结扎右侧颈总动脉,在缺氧环境下(氧体积分数为80 mL/L)放置2 h。