Methods Diabetes mellitus was induced in rats by intraperitoneal injection of streptozotocin and high-fat feeding for 8 weeks.

• 方法链脲菌素腹腔注射及经高脂饮食喂养8周形成糖尿病大鼠内膜增生模型，分别取外周血、动脉壁以及脾脏组织，并制备组织单细胞悬液。