Methods CMCNa was used as a base to prepare gel with tinidazole and sparfloxacin.The content of two drugs in the gel were directly determined by dualwavelength UV spectrophotometry without separation.

• 方法以替硝唑和司帕沙星为主药、羧甲基纤维素钠为基质制备复方替硝唑凝胶剂,采用双波长紫外分光光度法不经分离直接测定两主药含量,将制剂用于阴道感染的治疗。