Methods Animal model of chronic fluorosis in lactating rats was established with administration of large dose of fluoride in drinking water.

• 方法以饮用含氟水的方法复制哺乳期大鼠慢性氟中毒模型,对脑干中缝核群5-羟色胺神经元进行免疫细胞化学定性、定量研究。