Methods 24 S-D rats were performed cecal ligation and puncture(CLP) to induce sepsis. At the time of 0,12,36 and 72 hours after CLP,the rats were killed.

• 方法24只SPF级SD大鼠采用盲肠结扎穿孔术(CLP)复制脓毒症模型,分别于CLP后0、12、36和72 h颈椎脱臼法处死大鼠,取肺组织。