Metabolic rate of caffeine in the whole blood was determined by HPLC to study the effect of hedyotis diffusa willd on the activity of rat liver CYP 1A2;

• 用HPLC法测定非那西丁的代谢率,确定白花蛇舌草水提取物对大鼠肝微粒体CYP 1A2活性的影响。