Metabolic indexes are significantly different in different period of T1DM in children; particularly,insulin dosage can be calculated from C-peptide/FBG by the regression equation of them and can be adjusted according to FBG and ISF.

• 对1型DM儿童可依据糖代谢指标的变化调整胰岛素的用量,其中,C肽/FBG作为INS用量调整的参考依据最准确,可根据二者之间的回归方程由C肽/FBG粗略计算胰岛素用量,并根据餐前血糖及胰岛素敏感指数对胰岛素用量进行调整。