Medicine intermediate N-ethylethylenediamine(NEED) was synthesized from acrylamide and ethylamine by addition reaction and Hofmann rearrangement.

• 以丙烯酰胺为起始原料,经乙胺加成后,再经Hofmann重排两步反应后合成了药物中间体N-乙基乙二胺(NEED)。