Meanwhile it is suggested that bFGF and EGF can promote the BMSCs proliferation and shorten population doubling time and BDNF and RA is able to increase the expression of the special antigen of mature nerve cell and glia cell;

• bFGF和EGF能在体外促进BMSCs增殖，缩短群体倍增时间，BDNF和RA能诱导BMSCs来源的神经干细胞成神经元样和神经胶质细胞样细胞，并表达相应的细胞标记物(NeuN或GFAP);