Matrix metalloproteinases (MMPs) can regulate the tumour microenvironment, and their expression and activation is increased in almost all human cancers compared with normal tissue.

• 基质金属蛋白酶（MMPs）能够调节肿瘤的微环境，与正常组织相比，在几乎所有的人类癌症中都发现有基质金属蛋白酶的表达和活性。