MVA lactone has been synthesized from simple and cheap chemical reagents , such asacetone, formaldehyde, acid anhydride, tert - butanol and 2 - chloro - propan, The overallyield is 45%.

• 本文采用实验室常见且价廉的丙酮、甲醛、乙酸酐、叔丁醇及异氯丙烷为原料，通过醛酮缩会、酸酐酰化、格氏反应等方法，合成了甲瓦龙酸内酯，收率达到35%25-45%25。