METHODS: Model establishment: Wistar rats were administrated AS feeds (including 10% yolk powder, 5% lard, 0.5% bile salt and 85% basic feed) for 3 months.

• 川芎嗪(由预新国际龙源药业有限公司提供；批号20041204)。 方法:造模:Wistar大鼠饲喂动脉粥样硬化饲料(蛋黄粉10%25、猪油5%25、胆盐0.；5%25、基础饲料85%25)；喂服3个月。