METHODS The inhibitory effects of different dosages of LNNA by ig and ip administration on abstinent syndrome induced by naloxone in morphine-dependent mice were observed,and tolerance of pain was determined by hot plate method.

• 方法 :采用小鼠戒断模型 ,观察不同给药途径 (ip和ig) ,不同剂量的LNNA对吗啡依赖小鼠戒断综合症的治疗效果。