METHODS Sulfonylurea functional groups were introduced into the structure of coumarin, and the hypoglycemic activity of the target compounds was measured.

• 方法:运用拼合原理,以具有降血糖活性的香豆素为母环,在其结构中引入磺酰脲基团并测定目标化合物对小鼠的降血糖效果。