M-CSF can induce human osteoclast formation and stimulate them to differentiate,survive and participate bone resorption caused by mature osteoclasts,and inhibit the apoptosis of osteoclasts.

• M-CSF可诱导人破骨细胞形成,刺激其分化、存活,参与成熟破骨细胞对骨的吸收作用;