LRP induced cancer cells resist to multidrugs in direct or indirect ways.LRP may be of predictive value in treatments of carcinomas,and high expression of LRP was correlated with bad prognosis.

• 肺耐药蛋白直接或间接介导了多种肿瘤细胞多药耐药的产生,可作为治疗预后评判的指标,肺耐药蛋白高提示预后不良。