L-arginine and NMMA could upregulate and down-regulate this suppression respectively.Indomecine, a specific blocker of cyclooxygenase, also markedly attenuated the Con A-stimulated SPL proliferation.

• 消炎痛使抑制率下降到62.；3%25，但L-精氨酸能明显增强此抑制作用，而NMMA能减弱此抑制作用，并且消炎痛与NMMA有相互叠加的作用。