L-arginine administered in the early stage of ischemia can upregulate the NO, which can inhibit the expression of E-selectin.

• 大鼠脑缺血早期使用左旋精氨酸可以增加缺血区域NO含量，减少缺血再灌注早期E-选择素的表达和中性粒细胞的浸润。