L-Asp6-Ibuprofen was prepared by mixture anhydrides methods and DCC/HOBt methods.The benzyl group of the product was deprotected by catalytic hydrogenation.

• 方法使用混合酸酐法制备L-天冬氨酸六肽,分别用混合酸酐法和DCC法连接布洛芬,氢化还原得产物。