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Janus tyrosine kinases Janus 酪氨酸激酶
Roles of receptor tyrosine kinases, integrins, and Shc. 外文期刊 Mechanotransduction in response to shear stress.
Tyrosine kinases are involved in the pathogenesis of most cancers. 酪氨酸激酶参与了大部分肿瘤的发病。
Janus protein tyrosin kinases 1 (JAK1) JAK1
However, few tyrosine kinases have been shown to have a well-defined pathogenetic role in lymphomas. 然而，，很少有酪氨酸激酶在淋巴瘤的发病中有比较明确的作用。
In addition, WBZ_4 also inhibited JNK tyrosine kinases - an effect that is known to further protect the heart. 此外， wbz_4也能抑制活性的酪氨酸激酶-大意是众所周知的，以进一步保护心脏。
Tyrosine kinases are attractive as targets in the research of therapeutic agents, not only against cancer, hut also against many other diseases. 在包括癌症和其他许多疾病的治疗研究中，酪氨酸激酶都是研究的目标和对象。
The name is soluble f-m-s-like tyrosine kinase one? 这种蛋白质叫做可溶解fms样酪氨酸激酶一，
Protein tyrosine kinases play an important role in signal transduction pathways in regulating a number of cellular functions. 蛋白质酪氨酸在一系列细胞活动的信号转导途径中起着重要的作用。
But imatinib is known to cause heart problems in some people because it also switches off tyrosine kinases in the ABL family. 但伊马替尼是众所周知的导致心脏问题，在一些人，因为它还要开关小康酪氨酸激酶在abl的家庭。
The epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases have close connection with the initiation, progression and progn osis of various malignancies. 表皮生长因子受体(EGFR)家族的受体酪氨酸激酶与多种恶性肿瘤的发生、发展及预后等密切相关。
Moreover, non-cytotoxic agents such as small molecules targeting receptor tyrosine kinases and intracellular signaling pathways have been used in the clinical field. 替莫唑胺及亚硝基脲类药物耐药性得到了部分解决以及非细胞毒性药物如酪氨酸激酶抑制剂及细胞间信号传导通路抑制剂在临床中的应用。
Is PDGF tyrosine kinase inhibitor effective in pancreatic cancer? PDGF受体酪氨酸激酶抑制剂在胰腺癌中是否有作用?
Sorafenib, a novel, oral multi-kinase inhibitor, targets on serine/threonine and receptor tyrosine kinases of the tumor cells and vasculature; blocks the signal transconduction and inhibits tumor growth. 摘要索拉非尼是首个口服多激酶抑制药，靶向作用于肿瘤细胞和肿瘤血管上的丝氨酸和（或）苏氨酸及受体酪氨酸激酶，阻断信号传导，抑制肿瘤生长。
IMPLICATIONS: Sevoflurane exerts a preconditioning effect against ischemic cell death in the rat acute hippocampal slice, depending on both tyrosine kinases and duration of ischemia. 七氟烷对抗大鼠海马切片的缺血细胞死亡的预处理效果，依靠络氨酸激酶和缺血的持续时间。
The inhibitor of VEGF receptor tyrosine kinase was introduced in detail. 详细介绍了VEGF受体酪氨酸激酶抑制剂的研究进展。
Sunitinb is a novel multitargeted receptor tyrosine kinase inhibitor. 苏尼替尼是一种新型的多靶点酪氨酸激酶抑制剂。
The ABL gene encodes a tyrosine kinase whose activity is tightly regulated. ABL基因编码一种活性受到严格调控的酪氨酸激酶。
Members in this pathway include the Janus kinases (JAKs) family containing JAK1, JAK2, JAK3 and TYK2 and the STATs (signal transducer and activator of transcription), which contain STAT1 to STAT6. 然而它所影响范畴包括了细胞增生、细胞命运的决定、组织的发育以及免疫系统反应。哺乳类动物中，JAK家族有JAK1, JAK2, JAK3 和TYK2，STAT家族则有STAT1-6。