It has been hypothesized that destruction of biliary tract in primary biliary cirrhosis (PBC) would be closely correlated with proliferation of autoreactive T cell.

• 自身反应性T细胞的增殖与原发性胆汁性肝硬化(Primary biliary cirrhosis，PBC)中胆管特异性损伤密切相关，并在PBC的发生、发展中起重要作用。