It emphasized the importance of closing the tube with proper concentration of heparin, skin disinfection, cotton gauze, improvement of tube materials quality and the suitable indwelling time.

• 强调选择合适浓度的肝素溶液封管、有效的皮肤消毒方法、棉质纱布的应用、导管材料的改进、合适的置管时间等的重要性。