It also is related to bone marrow structural damage resulting from tumor invasion,large proliferation of granulation or fibrous tissue,which often affect hemopoiesis.

• 亦与骨髓被恶性肿瘤细胞浸润、肉芽和(或)纤维组织大量增生，使骨髓结构破坏，影响红系造血有关；