Irbesartan could decrease the heart injury in diabetic rats.And the mechanisms might be that irbesartan can reduce the MDA levels and improve SOD activity in STZ-induced diabetic rats.

• 伊贝沙坦能减轻糖尿病大鼠心脏损害的进展，其机制可能与伊贝沙坦抑制糖尿病大鼠脂质过氧化反应和提高抗氧化能力有关。