Intrahepatic cholestasis of pregnancy. (ICP) occur at middle later or term pregnancy with skin pruritus, jaundice and high bile acids level of women, the fetal prognosis is worse than maternal.

• 背景及目的：妊娠肝内胆汁淤积症(ICP)是发生于妊娠中晚期以皮肤瘙痒、黄疸和血清胆汁酸升高为特征的疾病,孕妇预后较好，但胎儿预后不良，可导致早产、胎儿窘迫及胎死宫内，使围产儿病率及围产儿死亡率提高。