In vitro study, HSV-tk-expressed-cells prove to be more sensitive to ACV than parent cells. The sensitivity of SHGLNTK and NBALNTK to ACV is 1000 and 500 times that of their parent cells respectively.

• 体外实验证实，表达HSV-tk次的细胞对ACV的敏感性明显高于未修饰的亲本细胞，SHGLNTK、NBALNTK细胞对ACV的敏感性分别是其亲本细胞的1000、500倍。