In vitro amoxicillin release behavior was investigated using paddle method andamoxicillin concentration determined by UV spectrophotometry. In pH 7.8phosphate buffer, amoxicillin could be sustainedly released from 30% at 2 hrs to 90%at 12 hrs.
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释义
建立了紫外分光光度法测定粘附微球在 pH7.;8 磷酸盐缓冲液中阿莫西林释放度的方法;阿莫西林粘膜粘附微球 2h 释药 30%25左右;并能缓释至 12h;释药量达 90%25。
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