In this study penicillin hapten was respectively coupled with BSA and OVA to synthesize PEN-EDC-BSA and PEN-EDC-OVA complete antigen applying CDI.

• 本研究分别以牛血清白蛋白(BSA)、卵清蛋白(OVA)为蛋白质载体,采用碳二亚胺法(CDI)将半抗原青霉素钠(PEN)分别与 BSA、OVA 偶联,合成了完全抗原 PEN-EDC-BSA 和 PEN-EDC-OVA。