In this review, the strategy and progress towards development of a HIV vaccine, and the present research status and applied prospects of SIV/SHIV macaque model in HIV vaccine research were summarized.

• 本文简要介绍了AIDS疫苗的研发策略、研发概况以及SIV/SHIV猕猴模型在HIV疫苗中的应用，并对其中存在的问题及其应用前景进行了探讨。