In this article we reviewed the POAG-related genes, especially the three well-known virulence genes of MYOC, OPTN, WDR36, in terms of their locations, structures, functions, mutations, etc.

• 本文就POAG的相关基因,尤其是已确认的MYOC,OPTN,WDR36三种致病基因的定位、结构、功能和突变等方面进行综述。