In these studies the use of clinical signs, reduced urinary concentration capacity, elevated BUN, and elevated plasma creatinine have limited ability to detect efficacy of protein restriction.

• 这些研究使用临床特徵，降低尿浓度的容量，提高血中尿素氮，和增加血浆肌酸酐，以限制其功能来约束蛋白质摄取的功效。