In the group of methotrexate, 14 have nausea or vomiting (27.45%), 3 have Rash or mouth ulcers (5.88%), 1 have hematochezia (1.96%).

• 甲氨蝶呤组恶心呕吐14例(27.；45%25)，皮疹及口腔溃疡3例(5