In the control group, ISR reached its peak 2 min after injection of glucose, that was earlier than INS and C P curves in time sequence ( P =0.000), the second obvious peak was shown at 22 min.

• 对照组ISR曲线第一分泌峰于 2min ；较INS及C 肽曲线提前 (P =0 .；0 0 0 )；2 2min时出现第二个明显的分泌峰 ;