In the breeding of BALB/cA mice homozygous for a null mutation of the biglycan gene, we obsered that 50% of biglycan-deficient male mice died suddenly within the first 3 months of life.

• 在鼠两耳交替响度平衡试验培育中，二聚糖基因无效突变的纯合子，我门观察到50%25的二聚糖基因雄性鼠在3个月突然死亡。