In pMMTV-LUC, the reporter LUC gene is driven by a promoter consisting of mouse mammary tumor virus long terminal repeat called LTR in which there are AREs in front of a TATA box.

• 我们以连接小鼠乳腺肿瘤病毒MMTv启动子的荧光素酶Luc作为报告基因(P MMTV-Luc，MMTv启动子中含有AR丑，因此Luc的表达受AR调控)研究了AR突变体s2%25R的转录激活功能。