In mice that lacked beta-catenin fracture healing was inhibited, whereas in mice expressing an activated form of beta-catenin bone healing was accelerated.

• 而在缺少了此种分子信号路径的老鼠中，骨折的愈合过程则停止了，相反的，在此基因表达活跃的老鼠体内，骨骼生长的过程则大大加速。