In humans and other vertebrates, the biological activity of progesterone is mediated by modulation of the transcriptional activity of two progesterone receptors, PGR-A and PGR-B.

• 在人类和其他脊椎动物中，孕酮的生物活性主要是通过两个孕酮受体PGR-A和PGR-B转录活性的调节来介导。