In early developing ESCMs, the type 2 inositol triphosphatereceptor (IP3R2) inhibitor 2-APB inhibited the amplitude of Ca2+ transient and itsinhibitory effect decreased with cardiac development.

• 在分化发育的各不同阶段,分离出能自主收缩的心肌细胞,检测了各Ca~(2+)释放通道或受体的在发育过程中的表达;