In consequence, there exist profound differences between normal skin and TE skin, with the later having no skin adnexa, such as hair follicle, sebaceous gland and sweat gland and so on.

• 目前的组织工程皮肤的种子细胞来源主要是皮肤真皮成纤维细胞和表皮角质形成细胞,由此构建的组织工程皮肤没有毛囊、皮脂腺等皮肤附属器官,在组织结构上与正常皮肤组织仍有较大差异。