In both cases CCA demon- strated a complex translocation,t(6;8;21) (p22;q2;q22),which was confirmed by interphase and meta- phase FISH and AML1/ETO fusion transcript was detected by RT-PCR.

• 2例患者常规细胞遗传学分析显示均存在 t(6;21;8)(p22;q22;q22),间期和中期 FISH 证实了核型结果; RT-PCR 检测到 AML1/ETO 融合基因转录本;