In acute experiment, active ERK2 content decreased remarkably at 30 and 60 min, and returned to normal level at 120 min, while control group had no obvious changes.

• 海马片培养中 ,对照组活化的ERK2含量基本保持不变 ,铅中毒组在 30和 60min时分别下降了 68%25和 33%25 ,1 2 0min后恢复到正常水平。