IMPLICATIONS: Local anesthetic-related methemoglobinemia is a recurring problem and may lead to life-threatening events. The clinical use of benzocaine and prilocaine needs to be reassessed.

• 局部麻醉药相关的高铁血红蛋白症是一个再发性问题并且可能威胁生命。临床应用苯坐卡因和丙胺卡因需要得到再评估。