ICAM-1 is an accessory molecule stabilizing the T-cell receptor-mediated binding between antigen-presentingcells and T lymphocytes, and serves as a cofactor in the activation of the cellular immune response.

• ICAM-1能辅助稳定T细胞受体介导的抗原呈递细胞（Antigen-presenting cells，APC）和淋巴细胞的结合，是细胞免疫协同激活因子。