Hydroxy-acetophenone was synthesized from phenol and acetic anhydride by esterification and Fries rearrangement reactions with the yield of 58.5%(content 98.68% of 4-hydroxy-acetophenone).

• 以苯酚和乙酐为原料 ；经过酯化反应和 Fries重排反应合成了对羟基苯乙酮 ；收率 5 8.；5%25；纯度 98