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- Methods: Human epidermal keratinocytes(cell line HaCaT) were cultured in vitro. After treated with certain concentration of arsenic,the expressions of CDK2,CDK4 and cyclin-E were measured by immunoblot test. 方法:以体外培养的角质形成细胞株为对象,一定浓度砷剂处理细胞后,用免疫印迹方法研究HaCaT细胞周期蛋白依赖激酶2(CDK2)、周期蛋白依赖激酶4(CDK4)和细胞周期蛋白E(Cyclin-E)的表达情况及砷剂对其表达的影响。
- Human epidermal keratinocyte 角质形成细胞
- Cytotoxicity of Perchloroethylene on Normal Human Epidermal Keratinocytes 四氯乙烯对人原代角质形成细胞的细胞毒性作用
- It will increase the water content of the stratum corneum, so as to reduce the extent of the epidermal keratinocyte. 提高角质层的水分含量，使表皮角质化的程度减弱。
- Objective To study the expression of CD44V6 in human epidermal tumours and malignant melanoma. 目的研究CD44V6在鳞状细胞癌、基底细胞癌和恶性黑素瘤的表达。
- Keywords perchloroethylene;human epidermis keratinocytes;cytotoxicity; 四氯乙烯;角质形成细胞;细胞毒性作用;
- MYC in human epidermal stem cells can stimulate differentiation rather than uncontrolled proliferation. 人类上皮干细胞中的MYC可以刺激分化而非无法控制的增殖。
- As the analogues of human epidermal growth factor recptor, HER2/neu overexpression can activate Ras/Raf/MEK/MAPK pathway. HER2/neu作为表皮生长因子受体家族的一员,在过表达的情况下能够激活Ras/Raf/MEK/MAPK通路,但是否通过此通路对乳腺癌细胞内p53表达产生影响,进而影响细胞的增殖和凋亡,目前亦未见报道。
- Objective To study the effects of podophyllotoxin solid lipid nanoparticles (POD-SLN) on the proliferation of human epidermal cells in vitro. 目的研究鬼臼毒素固体脂质纳米粒(POD-SLN)对人表皮细胞增殖的影响。
- A precursor of itamin E has been shown to be effectie against breast cancer cell lines which oer-express human epidermal growth factor receptor (HER2). 现有的研究已表明，维生素E原能够有效地对抗那些过度表达人类表皮生长因子受体(HER2)的乳腺癌细胞系。
- OBJECTIVE To explore the therapeutic effect and possible adverse reaction of recombinant human epidermal growth factor (rhEGF) for common kinds of wounds in clinics. 目的 观察重组人表皮生长因子 (rhEGF)对临床各种常见创面的治疗作用和副作用。
- Strong immunoreactivty of TARC was observed in the epidermal keratinocytes of 11 cases of the lesional skin of patients with BP. TARC在大疙性类天疙疮皮损中表达明显上调，12例大疙性类天疙疮有n例表皮均有不同程度的表达(1+一2+);
- Epidermal keratinocytes produced angle, such as cattle, sheep skin sheath and rhinoceros skin Kok, dermal bone formation angle, such as the Antlers. 表皮产生角质角，如牛、羊的角质鞘及犀的表皮角，真皮形成骨质角，如鹿角。
- EGF PE40, expressed by ?E. coli, ?is the chimeric protein of human epidermal growth factor (EGF) and PE40 which is recombinant protein of the translocated subunit and killing subunit of Pseudomonas exotoxin A (PEA). :egf-PE4 0是由人表皮生长因子 ( egf)基因与绿脓杆菌外毒素 A( PEA)的跨膜亚单位和毒力亚单位( PE4 0 )基因融合 ,在大肠杆菌内表达的重组毒素。
- Secretion of tPA in differentiation of epidermal keratinocyte 表皮角质形成细胞分化中tPA分泌的研究
- Therefore,we observed the changes of LCs in cultured human epidermal cells (ECs) by ATPase staining,HLA-Dr monoclonal antibody indirect immunofluoresence and enzyme labelling avidin-biotin complex (ABC) staining. 本研究系利用ATPase染色,抗人HLA-Dr抗原单克隆抗体间接免疫萤光及免疫酶标(ABC)染色,观察了人表皮细胞(Ecs)培养中Lcs的密度及形态变化。
- Cetuximab is a recombinant, human/mouse chimeric monoclonal antibody that binds to the extracellular domain of the human epidermal growth factor receptor on both normal and tumor cells. 西妥昔单抗是一种重组人源性/鼠源性嵌合性单克隆抗体，能结合正常细胞和肿瘤细胞上的人表皮生长因子受体的胞外域。
- AIM:To observe the effect on DNA content and cell cycle of back wounds by exogenous recombinant human epidermal growth factor(rhEGF) mixed with bletilia striata gelatin(BSG) in rabbits,and to explore the underlying mechanism. 目的:观察白芨胶作为外源性重组人表皮生长因子载体对兔背部创面表皮细胞DNA含量及周期的影响,并探讨其机制。
- This study was established in serum free condition. The effects of epidermal growth factor (EGF),bovine pituitary extract (BPE), and ethanolamine (Etha) on the DNA synthesis of human epidermal cells were determined by thymidine incorporation. 采用无血清培养系统，以3H－TdR掺入法测定表皮生长因子（EGF）、牛垂体提取物（BPE）和乙醇胺（Etha）对人表皮细胞DNA合成的影响。
- Methods This study was established in serum-free condition. The effects of epidermalgrowth factor (EGF), bovine pituitary extract (BPE), and ethanolamine (Etha) on the DNA synthesisof human epidermal cells were determined by (3H) thymidine incorporation. 方法采用无血清培养系统，以3H－TdR掺入法测定表皮生长因子（EGF）、牛垂体提取物（BPE）和乙醇胺（Etha）对人表皮细胞DNA合成的影响。
